2021-02-25 20:41:08 | Germans Clamor for Covid Vaccines, but Shun AstraZeneca’s Offering


Story by: Melissa Eddy The New York Times World News

BERLIN — At the start of the year, many Germans were complaining about a shortage of coronavirus vaccines that could free them from onerous lockdowns and limited social lives. Just weeks later, many are now upset that they’re not getting the vaccine they want.

As people around the world clamor for inoculations, and many countries have seen severe shortages, a preference for a vaccine developed by the German company BioNTech with Pfizer, is causing a pileup in Germany of the shot developed by AstraZeneca, a British-Swedish company, according to state health officials.

Many people — including health workers — are skipping appointments or refusing to sign up for the AstraZeneca shot, which they fear is less effective than the Pfizer-BioNTech vaccine, the officials say. As a result, two weeks after the first delivery of 1.45 million doses of the AstraZeneca vaccine arrived in Germany, only 270,986 have been administered, according to data collected by the public health authority, the Robert Koch Institute.

“The point is that we have a German-made product that is the market leader, but we are not able to get it,” said Michael Breiden, 53, a night nurse in a psychiatric hospital in the western state of North Rhine-Westphalia. He said he would prefer the Pfizer-BioNTech shot, but would take the AstraZeneca one if it meant getting immunized more quickly.

The rejection of the AstraZeneca vaccine has been fueled by weeks of negative coverage about it in the German media, which has portrayed it as “second-class,” citing its lower efficacy rate compared with Pfizer-BioNTech, and reporting stories of people suffering adverse reactions.

Clinical trials do suggest that Pfizer’s efficacy, at 95 percent, is higher than AstraZeneca’s, which is between 60 and 90 percent depending on factors such as the spacing of doses. Still, it is difficult to directly compare shots unless they are tested head-to-head in the same trial. And many health professionals suggest getting whichever vaccine is available first since Covid poses such health risks.

All the leading vaccines offer strong protection against severe disease and death, but as the overall efficacy rates show, some appear to do better than others in protecting against any form of the disease. Even mild or moderate Covid cases can lead to long struggles with symptoms.

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Widespread skepticism about vaccines in Germany has exacerbated people’s reluctance to take the AstraZeneca shot. Medical and other frontline workers also have expressed resentment about being given unused AstraZeneca shots, instead of the Pfizer-BioNTech one, saying it showed a lack of respect after their efforts to help the country fight the pandemic over the past year.

The rejection of the AstraZeneca vaccine has caused delays in a mass vaccination campaign that was already struggling with bureaucratic and logistical hurdles. That has raised concerns that, with new cases of coronavirus infection increasing, even as Germany remains largely locked down, failure to immunize enough people quickly enough could stymie efforts to return the country to normal life.

“Vaccinating fast is the order of the day,” Germany’s president, Frank-Walter Steinmeier, told citizens in Bavaria during a videoconference on Thursday, stressing that all three vaccines in use in Germany had been approved by the European Medicines Agency and were trustworthy.

“I personally have little sympathy for the reluctance to use one vaccine or another,” he said. “This is a first-world problem, certainly for those who are still waiting for their first vaccination and even more so for people in countries who might not even have the prospect of receiving a first inoculation this year.”

President Emmanuel Macron of France, who had previously dismissed the AstraZeneca vaccine as questionably effective for older age groups, told reporters on Thursday that he would take it himself, responding to reports of the shot facing skepticism in several parts of Europe.

The problem runs deeper than just AstraZeneca. According to a survey by the Bertelsmann Foundation, a third of Germans say they would not get vaccinated, regardless of who made the shot. In addition to AstraZeneca, Germany is also administering the vaccine made by Moderna, an American company, without problems or resistance. The vaccine has an overall efficacy of 94.5 percent.

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AstraZeneca’s vaccine has been generating negative headlines in Germany since January, when the company said it would significantly cut planned deliveries to the European Union. Days before the first doses were delivered, Germany’s vaccine commission recommended that the AstraZeneca shot be given only to adults up to age 65, citing a lack of sufficient data on its efficacy in older people, advice that was followed by Chancellor Angela Merkel’s government.

Then several hospitals were forced to temporarily stop administering AstraZeneca shots after a number of people called in sick the day after their inoculations after experiencing what are considered normal reactions to the vaccine. Although the hospitals have since resumed vaccinations at a slower rate, the headlines created further uncertainty.

Dr. Lisa Koch, a dentist from Berlin, said she was surprised at the number of young workers in her office who said they would not get vaccinated, although their jobs meant spending several hours a day around unmasked patients. Only the three dentists and another staff member agreed to be immunized, she said.

“They think that the vaccine is not safe, that it won’t work, or could even harm them,” she said, adding that most of those rejecting the jabs were in their 20s or 30s. “They are all a bit younger, maybe they have the feeling that they don’t need it.”

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Ursula von der Leyen, the president of the European Commission, who is also a medical doctor, said that several months ago, before the vaccines had been through their final clinical tests, the hope was that they could reach at least 50 to 70 percent efficacy.

“I would not hesitate to get vaccinated with AstraZeneca any more than I would with other vaccines from BioNTech-Pfizer or Moderna,” Ms. von der Leyen told the Augsburger Allgemeine newspaper.


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Source References: The New York Times World News

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