Oxford trial to test efficacy of mix of Covid vaccines for individuals
Volunteers are being sought for a world-first trial to establish the efficacy of giving people a first dose of one vaccine and a second dose of a different vaccine.
The trial, which is being run by Oxford University and is funded by the government’s vaccine taskforce, has been described by ministers as “hugely important”.
It will recruit 820 people over the age of 50 who have not yet had a vaccine, to receive a first dose of either the Oxford/AstraZeneca vaccine or the Pfizer/BioNTech vaccine. Some people will then get an alternative vaccine at a second appointment within 12 weeks, and others will get the same vaccine again.
Public Health England’s Green Book on vaccinations already tells the NHS that in exceptional circumstances if people arrive for their second dose and the vaccine they originally had is not available, they can be given a different one:
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